However, presence of other co-morbid conditions/confounders warrants cautious interpretation. To conclude, serum ferritin level may serve as an important biomarker which can aid in COVID-19 management. Patients requiring ICU and mechanical ventilation had higher serum ferritin levels compared to those who didn't. (RevMan 5.
![revman 5 meta regression revman 5 meta regression](https://www.mdpi.com/ijerph/ijerph-15-01121/article_deploy/html/images/ijerph-15-01121-g003.png)
meta-analysis one can use an adaptation of the simple logistic regression. We included 24 studies, 11 randomized clinical trials and 13 observational cohorts. here that a random-effects MH approach is also implemented in RevMan 5. In meta-regression, high heterogeneity observed could be attributed to difference in “mean age” and “percentage of male sex”. Metaregression was then applied to explore the sources of betweenstudy heterogeneity. Conclusion: Physicians should be more aware and take extra precautions with diabetes patients who use insulin therapy. Non-survivors had higher serum ferritin level compared to survivors. Meta-regression showed that the association was influenced by age (p 0.008), but not by diabetes (p 0.423), and cardiovascular disease (p 0.086). In meta-regression, high heterogeneity was observed could be attributed to difference in “mean age”, and “percentage of population with concomitant co-morbidities”. Severe to critical COVID-19 patients showed higher ferritin levels compared to mild to moderate COVID-19 patients. Compared to control (COVID-19 negative), higher ferritin levels were found among the COVID-19 patients. Metaanalysis and metaregression was carried out using metaphor “R” package. Results: In total, 17 studies were included, and the overall number of subjects with and without AMS was 18, respectively. survivor, organ involvement, ICU and mechanical ventilation requirement) were included (total 9 literature databases searched). Meta-regression and subgroup analyses were conducted to identify sources of heterogeneity using Stata 14.2 and RevMan 5.0. Studies evaluating serum ferritin level in different clinical contexts (COVID-19 vs. This current metaanalysis evaluates serum ferritin level in different severity levels in COVID-19. A basic funnel plot is available in most programs except in. Publication bias analyses help researchers to estimate the threat of unpublished or undiscovered research reports for the validity of a meta-analysis.
![revman 5 meta regression revman 5 meta regression](https://media.springernature.com/lw685/springer-static/image/art%3A10.3758%2Fs13428-020-01360-0/MediaObjects/13428_2020_1360_Figc_HTML.png)
#Revman 5 meta regression pro#
However, many factors and co-morbidities can confound the level of serum ferritin. All tools, except RevMan, also feature meta-regression, although Meta-Essentials and MIX PRO only offer it for a single covariate.
![revman 5 meta regression revman 5 meta regression](https://predictivehacks.com/wp-content/uploads/2021/08/image-13-1024x215.png)
Ferritin is a known inflammatory biomarker in COVID-19.